Dear Colleagues,

It is a great pleasure to welcome basic and physician scientists to the 7th International Symposium on Kallikreins and Kallikrein-Related Peptidases (ISK2017), which will be held in Tours, France, from the 26th to the 29th of September, 2017.

From the discovery of Kallikrein-kinin system by E.K Frey, H. Kraut and E. Werle in the mid 20’s, Kallikreins and Kallikrein-related peptidases (KLKs) are becoming more and more attractive targets for scientists engaged in many areas of both academic and applied research. The KLK proteases are now known to be involved in various biological pathways that regulate skin desquamation, tooth enamel formation, kidney function, seminal liquefaction, immunity, synaptic neural plasticity, and brain function. Additionally to their physiological functions, KLKs have also been implicated in numerous malignancies through the regulation of several cellular processes, such as proliferation, survival, migration, and invasion of neoplastic cells and their involvement in cross-talks between cell populations present in the tumour microenvironment.

The 7th edition of the international symposium will propose a multidisciplinary program based on invited talks from international experts on the latest developments covering all areas of kallikrein research and clinical applications. In addition to the plenary lectures, this edition will also include many talks by trainees and young scientists, as well as poster sessions where attendees will be able to present their research in an interactive atmosphere. Therefore, you are all invited to submit your abstracts in order to be considered for an oral or a poster presentation.

The symposium will culminate in the conferring of prestigious awards of the FREY-WERLE and HENNER GRAEFF Foundations.

We believe that this symposium will contribute to further advance this interesting area of investigation and the discovery of novel applications of KLKs in diagnostics, therapeutics and personalized Medicine. In addition, this meeting will represent a fantastic opportunity for intense discussion between researchers interested in kallikreins and their related functions to share new ideas, point of views and stimulate new collaborations.

In addition to the scientific program, please join us for the welcome reception cocktail, gala dinner and trip in the famous “Vallée de la Loire” and the Royal Château of Amboise.

We look forward to seeing you, your colleagues and your families in Tours for a wonderful scientific meeting and an overall enjoyable experience.

Yours sincerely,

On behalf of the Organizing Committee

Yves Courty

ISK2017, President





Tours & the Loire Valley

Loire - David Darrault/ADT

Place Plumereau S.Frémont/ADT

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